Instem will be starting a read-across collaborative working group.
Tag archives: Read-across
Acute Toxicity in silico Battery
We are happy to have completed, after many years of work, a full battery of in silico models to evaluate acute toxicity. These models predict acute lethality by three routes of exposure (oral, dermal, inhalation), as well as skin and eye irritation/corrosion, and skin sensitization. They aim to support a variety of applications, including health, …
New read-across tool
Over the last year we have been working hard developing a new easy-to-use read-across solution that can instantaneously access over 200,000 chemicals with over 600,000 toxicity studies. The platform is able to integrate this data with chemicals and studies added by the user to conduct a read-across evaluation. It has been designed to directly support …
Predicting toxicity using read-across
Read-across is an example of a flexible in silico toxicology methodology whereby a toxicity prediction for a chemical (often referred to as the target compound) is made using experimental data on one or more similar analogs (often referred to as source compound(s)). This is a lengthy process highly reliant on an expert review of the …