We are delighted to be participating in an upcoming webinar organized by the Extractables and Leachables Safety Information Exchange (ELSIE) Consortium on the topic of a framework for sensitization assessment for Extractables and Leachables (E&L) on 22 September 2022, 9:30 – 11:00 AM ET1.
We will be describing the development of a representative database of E&L from the combined ELSIE Consortium and the Product Quality Research Institute (PQRI) published datasets. An analysis using chemical structure-based clustering will be outlined to show the similarities and differences between the two datasets. The presentation will also describe classes containing chemicals that were flagged as potentially mutagenic as well as potent (strong or extreme) dermal sensitizers by the Leadscope in silico tools.
Please get in touch if you would like to discuss this work in more detail (Glenn Myatt; firstname.lastname@example.org).